scglue.data.calc_hypo_score

scglue.data.calc_hypo_score(adata, mc_layer='mc', cov_layer='cov', chunk_size=1000)

Calculates the hypo-methylation score as X based on methylated counts and total coverage stored in separate layers

Parameters:

• adata (AnnData) – Input AnnData object

• mc_layer (str) – Layer storing methylated counts

• cov_layer (str) – Layer storing total coverage

• chunk_size (int) – Number of cells to include per chunk

Return type:

None