scglue.models.fit_SCGLUE

scglue.models.fit_SCGLUE(adatas, graph, model=<class 'scglue.models.scglue.SCGLUEModel'>, init_kws=None, compile_kws=None, fit_kws=None, balance_kws=None)

Fit GLUE model to integrate single-cell multi-omics data

Parameters

• adatas (Mapping[str, AnnData]) – Single-cell datasets (indexed by domain name)

• graph (Graph) – Prior graph

• model (type) – Model class, must be one of {scglue.models.scglue.SCGLUEModel, scglue.models.scglue.PairedSCGLUEModel}

• init_kws (Optional[Mapping[str, Any]]) – Model initialization keyword arguments (see the constructor of the model class, either scglue.models.scglue.SCGLUEModel or scglue.models.scglue.PairedSCGLUEModel)

• compile_kws (Optional[Mapping[str, Any]]) – Model compile keyword arguments (see the compile method of the model class, either scglue.models.scglue.SCGLUEModel.compile() or scglue.models.scglue.PairedSCGLUEModel.compile())

• fit_kws (Optional[Mapping[str, Any]]) – Model fitting keyword arguments (see scglue.models.scglue.SCGLUEModel.fit())

• balance_kws (Optional[Mapping[str, Any]]) – Balancing weight estimation keyword arguments (see scglue.data.estimate_balancing_weight())

Return type

SCGLUEModel

Returns

model – Fitted model object