scglue.genomics.generate_prot_guidance_graph

scglue.genomics.generate_prot_guidance_graph(rna, prot, protein_gene_match)[source]

Generate the guidance graph based on CITE-seq datasets.

Parameters:
  • rna (AnnData) – AnnData with gene expression information.

  • prot (AnnData) – AnnData with protein expression information.

  • protein_gene_match (typing.Mapping[str, str]) – The dictionary used to match proteins with genes.

Returns:

guidance – The guidance map between proteins and genes.